WebClínicamente, la expresión de BRMS1 se correlaciona con la supervivencia en el cáncer de mama y el carcinoma de pulmón de células no pequeñas. SDPR funciona como un supresor de metástasis en el cáncer de mama, potencialmente al cebar las células a la apoptosis. Las células cancerosas suprimen el gen a través de la metilación del ADN ...

Mining expression and prognosis of topoisomerase isoforms in …

Web10. okt 2024 · We found that TOP3A was overexpressed in the ALT-positive ATRX-wt tumors consistent with its amplification. We demonstrated the functional significance of these … Web1. jún 2024 · Human colon cancer HCT116 (RCB2979) cells were purchased from the RIKEN BRC. All cell lines used in this study were cultured in DMEM (Dulbecco's Modified Eagle Medium, Wako) complemented with 10% FBS ... TOP3A was the most likely to be linked to the above pathologic findings. marvel road salisbury md

Human topoisomerases and their roles in genome stability

WebTOP3A Gene - Somatic Mutations in Cancer Gene GRCh38 · COSMIC v97 Gene view The gene view histogram is a graphical view of mutations across TOP3A. These mutations are … WebTOP3A, a new partner gene fused to MLL in an adult patient with de novo acute myeloid leukaemia. human topoisomerase IIIalpha functions as a decatenase with the assistance … WebBloom syndrome is also associated with prenatal growth restriction, short stature, and microcephaly and results in higher cancer risk. Andrew Jackson, Carol-Anne Martin and colleagues have identified mutations in the TOP3A gene in people with a Bloom-like syndrome. These mutations affect the ability of the cells to untangle DNA during cell ... marvel rising theme song